Covid-19: Razvoj vakcine, imunitet i primena medikamenata

[omiljeni]

21 minutes ago, mustang said:

pa objasni gde gresim

 

https://en.wikipedia.org/wiki/Herd_immunity

 

tldr: pretpostavlja se da je za coronu potrebno da oko 70% populacije bude vakcinisano i epidemija će da nestane

problem je što će, ako se ovako nastavi, taj kolektivni imunintet nastati tako što će 70% populacije preležati bolest pre nego što naprave tu vakcinu

[Dankan Ajdaho]

1 hour ago, Tsai said:

Sta je najgora stvar koja moze da se desi ako je testirana vakcina losa? 

 

Može doći do raznoraznih lakših i težih nuspojava (dovesti ili biti okidač za druge bolesti ili stanja), biti neučinkovita ili biti uzrok bolesti protiv koje je napravljena. 

[mustang]

1 hour ago, omiljeni said:

 

https://en.wikipedia.org/wiki/Herd_immunity

 

tldr: pretpostavlja se da je za coronu potrebno da oko 70% populacije bude vakcinisano i epidemija će da nestane

problem je što će, ako se ovako nastavi, taj kolektivni imunintet nastati tako što će 70% populacije preležati bolest pre nego što naprave tu vakcinu

 

al ne znaju kojom se brzinom gubi imunitet, dal je 2,3,5 godina....

[keitel]

20 hours ago, TdEII said:

 

Pojedinačno, nadam se da će se izvući pravo i zdravo. U opštem, ništa ne može da se zaključi o efikasnosti hlorokina i kompletne terapije na osnovu jednog slučaja. Srećno, svakako.

 

Da li ima usvojenih stadarnih protokola, šta se sve proba u Srbiji, ako neko zna?

 

Hlorokin je u Srbiji u masovnoj upotrebi, u apotekama je nestašica a Stevanović je onomad upozorovao da se lijek ne smije koristiti na svoju ruku i da praktičnu svrhu ima tek u slučaju komplikacija. S druge strane, dosta ljudi na netu tvrdi da su im dali hlorokin čim im je dijagnostifikovan virus iako nisu bili u pitanju teži slučajevi.

Osim ovog tvog teksta nisam našao da se odustaje od njegove primjene, iako od početka upozoravaju na njegove kontraindikacije.

[Dankan Ajdaho]

http://rs.n1info.com/Zdravlje/a586020/Trkulja-Ima-razloga-za-optimizam-vakcina-mozda-u-prvoj-polovini-2021.html

[Strucnjak]

Supruga jutros dobila dobila mejl da njena firma globalno radi na nekoliko projekata u vezi vakcine. US Clinical trials kompanija

[Malkmus]

3 hours ago, Dankan Ajdaho said:

http://rs.n1info.com/Zdravlje/a586020/Trkulja-Ima-razloga-za-optimizam-vakcina-mozda-u-prvoj-polovini-2021.html

Pored gubitaka, recesije i svega što ide uz pomenuto, biće i debelih troškova za zaštitu i dezinfekciju. Čini mi se da oni po svakodnevno aktivnoj osobi izađu nešto manje nego jedna prosečna plata za godinu dana trajanja vanrednih okolnosti.

 

e. Uf, ovo je off, pošto je tema o vakcini. Pardon.

Edited April 6, 2020 by Malkmus

[Milosh76]

Biofarmaceutska kompanija Generium, locirana u ruskom regionu Vladimir, registrovala je prvi test za otkrivanje prisustva koronavirusa u roku od 40 minuta i sa tačnošću od 94 odsto, objavila je ta kompanija, prenosi Itar tas.

 

Preliminarna obrada traje 35 minuta, a za pojačavanje je potrebno dodatnih 25 minuta, pa bi uzorak trebalo da bude spreman za sat, navodi se u saopštenju i dodaje da je test 3. aprila već poslat u druge ruske regione.

 

Izvor iz kompanije navodi da su planovi da se od 80 do 90 odsto teritorije zemlje obezbedi testovima do kraja nedelje, kao i da se nedeljno proizvede pola miliona testova.

Edited April 7, 2020 by Milosh76

[vememah]

 

Quote

 

A second potential COVID-19 vaccine, backed by Bill and Melinda Gates, is entering human testing

Darrell Etherington@etherington / 9:44 pm CEST • April 6, 2020

 

A new COVID-19 vaccine candidate is entering Phase 1 clinical human testing today, after the U.S. Food and Drug Administration (FDA) accepted an application from Inovio Pharmaceuticals under the regulator’s Investigational New Drug program. Inovio plans to inject its first volunteer test subject with the INO-4800 DNA vaccine candidate it has developed, following promising results from preclinical studies performed on animals that did indicate increased immune response.

The Inovio DNA vaccine candidate works by injecting a specifically engineered plasmid (a small, independent genetic structure) into a patient so that their cells can produce a desired, targeted antibody to fight off a specific infection. DNA vaccines, while available and approved for a variety of animal infections in veterinary medicine, have not yet been approved for human use.

That said, Inovio’s work isn’t starting from scratch: The company previously completed a Phase 1 study for a DNA vaccine candidate for Middle East Respiratory Syndrome (MERS), where it showed promising results and a high level of antibodies produced in subjects that persisted for an extended period of time.

Inovio has been able to scale up quickly, developing and producing “thousands of doses” of INO-4800 in just a few short weeks in order to support its Phase 1 and Phase 2 trials. The company has done so in part thanks to backing from the Bill and Melinda Gates Foundation, as well as funding from other nonprofits and organizations. If clinical trials are successful, Inovio says it will be able to have up to one million doses of the vaccine ready by the end of the year, for use both in additional trials and for potential emergency use pending authorization.

This is the second vaccine to undertake Phase 1 clinical testing on human subjects: Moderna began its trial in mid-March. Inovio’s trial will be made up of 40 volunteers, all healthy adults selected via screening conducted at either Philadelphia’s Perelman School of Medicine at the University of Pennsylvania, or the Center for Pharmaceutical Research in Kansas City. It’ll span the next several weeks, and the company expects data around the immune responses from test subjects, as well as info pertaining to the safety of the treatment for humans, to be available by late this summer.

Any broad clearance or approval for use is still likely at least a year to 18 months away, but the pace with which human trials are beginning is still exceptional, so hopefully we won’t have to wait too much longer than that.

 

https://techcrunch.com/2020/04/06/a-second-potential-covid-19-vaccine-backed-by-bill-and-melinda-gates-is-entering-human-testing/

Edited April 7, 2020 by vememah

[Tsai]

Bill Gates je car

[goofs]

sto ukloniste one twitove?

[vememah]

Vest je detaljnija od tvitova.

[Bogotac]

Zlobnici bi rekli da vakcina vec postoji

[Joe D]

Mislis retardi?

[Tsai]

Just now, Joe D said:

Mislis retardi?

 

+1