Moja žena danas treća doza fajzer, pre šest meseci dva Sputnjika. Niko nije postavio pitanje.

49 minutes ago, vememah said:

Hrvatski ministar zdravlja:

 

 

Komentari na ovaj izveštaj .

Pa braća su gluplja od nas kolikogod to izgleda nemoguće.

Komentari su sve gore od goreg, tako da sam morala sve da pročitam.

Jedan jedini, neki splitski zet se pojavio sa nekim disonantnim upadicama.

Pomračenje mozga .

4 hours ago, Have_Fun said:

32000?

pretvorila se u fajzer o.O

Tri sedmice posle druge Pfizer doze imala sam antitela preko 40000, koliko ne znam, to je max za metodu. Znam za jos jedan takav slucaj. Mislim da sam imala koronu ni mesec dana pre prve doze, pa otud takav rezultat. 

@dùda

 

Naravno da su takve objave lepak za blesave antivaksere. Razumni nemaju šta da komentarišu taj podatak, mogu samo da ga prime k znanju.

Edited September 3, 20213 yr by vememah

@pt 2.0

 

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Antibody tests can't confirm if you're protected against COVID-19 after vaccination. Here's why.

 

People would like to know whether their COVID-19 vaccine is protective enough or a previous infection will keep them safe. Experts warned that taking an antibody test isn’t a good way to find out.

The tests were designed to show whether someone was recently infected with the coronavirus – not whether they have enough immune soldiers to prevent an infection.

The level of antibodies needed to provide protection isn't known. There are nearly 90 different antibody tests on the market, most of which measure something slightly different.

All that means it's anyone’s guess what the tests actually show about how protected someone is against COVID-19. Taking a test could give people a false sense of security, health experts said, or a load of unnecessary anxiety.

“(Antibody tests) were never developed and designed to detect or tell us anything about vaccine-induced protective immunity,” said Dr. Elitza Theel, director of the Infectious Diseases Serology Laboratory at the Mayo Clinic.
Antibody testing: What's out there and what it can tell you

The Centers for Disease Control and Prevention and the Food and Drug Administration recommend against using antibody tests to assess immunity after COVID-19 vaccination.

As of Aug. 18, the FDA has authorized nearly 90 different antibody tests, which range in price, to detect previous SARS-CoV-2 infection. Each test varies in which antibodies it detects, how well it detects them and how it reports its results.

“There are so many antibody tests out there that look for antibodies to different antigens,” Theel said. “Their performance characteristics differ ... there’s a lot of variability.”

A test’s sensitivity is its ability to recognize antibodies from the virus that causes COVID-19. Antibody tests can range from 85% to 99% sensitivity. Tests vary in specificity, which shows how likely a positive result is accurate.

                 

                    
Are cheap, plentiful home COVID tests the delta antidote?

                        

 

Not all of them look for the same antibodies. Some tests look for antibodies created from a part of the virus called the nucleocapsid protein.

These antibodies serve only as a marker of previous infection and don’t provide any kind of protection against the virus, said Dr. Reynold Panettieri, professor of medicine at Robert Wood Johnson Medical School in New Brunswick, New Jersey.

“It’s like a smoking gun,” he said. “The bullet is the virus, the smoke from the gun is the nucleocapsid … all it (says) is you’ve gotten an exposure, but it’s not going to help you prevent infection.”

Only antibodies that prevent the virus from entering a cell provide protection from infection.

The COVID-19 vaccines help the body create antibodies to the spike protein – and only the spike protein – which means people who have been vaccinated but not previously infected will show a negative result to a test that detects only antibodies from the nucleocapsid protein.

COVID-19 in kids: Are schools contributing to a spike in cases among kids? Partly, experts explain.

The 'Holy Grail' in terms of vaccines: Study showing antibody levels protecting against COVID-19 could speed creation of vaccines, boosters

Some tests specifically test antibodies to the spike protein, but this can also be deceptive as not all of the antibodies are protective.

Protective antibodies bind to the virus’s spike protein ACE2 receptor and prevent the virus from entering the cell.

“They bind to the virus in a way that they neutralize its ability to infect the cell,” Theel said.

Non-neutralizing antibodies may bind to other parts of the spike protein and have no effect on virus entry. Most tests don’t differentiate between the two types of antibodies.

A test that yields no spike protein antibodies doesn’t necessarily mean a person is unprotected from the virus, said Dr. Daniel Kuritzkes, chief of the division of infectious disease at Brigham and Women’s Hospital.

The body has experience producing those antibodies from the vaccine, he said. Even though there aren’t any detectable at the moment of testing, the body can quickly produce them again if it encounters the virus.

“With any vaccine, the response you measure in the blood is going to decrease over time after vaccination because the body isn’t being constantly exposed to the foreign protein,” Kuritzkes said. “But if they encounter the virus, the body can very rapidly have a recall, or a memory, response that is able to basically rush to the scene of infection and contain it.”
Antibodies don’t necessarily mean protection against COVID-19

Even if all commercial tests were able to detect neutralizing antibodies from COVID-19 vaccines, health experts said, immunity would not be guaranteed as it’s unclear what levels are needed to ensure protection against the virus.

“One of the biggest challenges and the reason why it’s not recommended to do post-vaccination antibody testing is because we still don’t have a defined correlate of protection,” Theel said. “The higher number, the more antibodies you have. But what number is clinically significant and associated with protection? We can’t say, yet.”

A preprint study  published Aug. 10 and not yet peer-reviewed sought to answer this question by looking for markers in vaccinated patients’ blood that would indicate immunity. Researchers found higher levels of neutralizing antibodies were linked with higher levels of vaccine efficacy.

Health experts said more studies are needed to confirm the study’s findings.

Measuring antibodies captures only one part of the immune system, Theel said.

T-cells are one of the most important players in cellular immunity. Whereas protective neutralizing antibodies bind to the spike protein to prevent the virus from entering the cell, T-cells search and destroy infected cells where the virus reproduces.
Johnson & Johnson booster vaccine generates a strong immune response
Johnson & Johnson says a second dose of its COVID vaccine generated a strong immune response.
Fox - 35 Orlando, Fox - 35 Orlando

The FDA authorized a test that detects a T-cell immune response to SARS-CoV-2 in March, but it’s not widely available.  

“So it would be a mistake for someone to measure an antibody response five or six months after the vaccine as not having immunity because your T-cell response is going to peak at that time, (and) it’s going to be more robust in generating immunity,” Panettieri said.

Kuritzkes said most Americans shouldn’t depend on antibody tests to assess immunity after COVID-19 vaccination, but there are a few exceptions. One includes people who have an immunocompromising condition or take immune suppressing medications.

If a spike protein antibody test yields no antibodies in a person who has a compromised immune system a month after getting fully vaccinated, it’s safer to assume that person did not build a sufficient immune response from the vaccine.

“In that situation, people need to be concerned that they may be susceptible to COVID-19 and should continue to take precautions such as wearing masks when they’re out and about and avoid large gatherings,” Kuritzkes said.

Though most fully vaccinated Americans can assume they have some protection against the virus, Kuritzkes said everyone should practice mitigation measures such as masking and social distancing amid the nationwide spike in coronavirus cases driven by the highly contagious delta variant.

“In the current surge, everybody should be taking precautions regardless of what an antibody test is showing them,” he said.

Follow Adrianna Rodriguez on Twitter: @AdriannaUSAT.

Health and patient safety coverage at USA TODAY is made possible in part by a grant from the Masimo Foundation for Ethics, Innovation and Competition in Healthcare. The Masimo Foundation does not provide editorial input.

 

 

On 20.8.2021. at 18:17, cedo said:

ne znam da li ste ovo kacili ... vredi procitati

 

 

Israeli data: How can efficacy vs. severe disease be strong when 60% of hospitalized are vaccinated?

 

 

Ažurirana tabela:

 

 

Edited September 3, 20213 yr by vememah

 

 

 

 

 

 

  

On 2.9.2021. at 23:35, pufikaflafi said:

Sve mi se čini da oni očekuju da im Pfizer uradi studiju efikasnosti kombinovanja vakcina, a do tad verovaćemo transparentnim podacima sa kineskog sajta brata Sija.

Inače mesecima unazad se za svakog hospitalizovanog pacijenta obavezno uzima podatak o vakcinalnom statusu: da li je vakcinisan, kojom vakcinom i koliko doza je primio, tako da ne sumnjam u ministarstvu imaju podatke i mogu da izvedu zaključke.

Ali ne.... ovako, rovarimo u mraku, sve neke poluistine i poluinformacije kojima se samo čini usluga avaks pokretu. 

 

Evo zašto se ne mogu saznati podaci o efikasnosti vakcina u Srbiji i zašto se na režimskim medijima vrlo retko može čuti poziv da se ne uzima Sinofarm kao treća doza:

 

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Sirovina za proizvodnju kineske vakcine "Sinofarm" stigla je u Beograd, a do oktobra će "Hemofarm" proizvoditi vakcinu za proces testiranja.

Ministar zdravlja Srbije Zlatibor Lončar je naglasio da će se u Srbiji proizvoditi ista vakcina kao u Kini, koja se trenutno pakuje u Ujedinjem Arapskim Emiratima, te dodao da su eksperti koji prate čitav proces testiranja i početak punjenja stigli u Srbiju i već rade sa domaćim stručnjacima na pripremi.

"Odmah nakon testiranja počinje i punjenje vakcine što će biti u oktobru. Plan je da se napuni oko šest miliona doza do kraja godine. Te doze će biti namenjene prvenstveno građanima Srbije, a ako bude višak i za izvoz u region", rekao je Lončar.

On je najavio da će u četvrtak, 9. septembra, biti postavljen kamen temeljac za novu fabriku za proizvodnju tih vakcina u Srbiji.

Ambasador Kine u Srbiji Čen Bo poručila je da je srećna što je saradnja dvije zemlje dostigla novi nivo time što će Srbija biti prva zemlja u Evropi koja će proizvoditi kinesku vakcinu, te podsjetila da je Srbija, takođe prva u Evropi počela i sa primjenom te vakcine.

blic.rs/vesti/drustvo/supstance-za-proizvodnju-sinofarma-stigle-u-beograd-loncar-do-kraja-godine-imacemo/8ec7hgz

Edited September 4, 20213 yr by vememah

U Srbiji će se proizvoditi ista vakcina kao u Kini, koja se trenutno pakuje u Ujedinjenim Arapskim Emiratima, rekao je Lončar, koji je supstance dočekao sa ambasadorkom Kine u Srbiji Čen Bo.

 

"Odmah nakon testiranja počinje i punjenje vakcine što će biti u oktobru. Plan je da se napuni oko šest miliona doza vakcina do kraja godine. Te doze će biti namenjene prvenstveno građanima Srbije a ako bude višak i za izvoz u region", poručio je ministar.

 

Dodaje da će 9. septembra biti postavljen kamen temeljac za novu fabriku za proizvodnju tih vakcina u Srbiji.

 

"Rok za završetak izgradnje fabrike je prvi kvartal sledeće godine, a proizvodiće se oko tri miliona doza vakcina mesečno. Nemamo naznake da će se korona uskoro zaustaviti, sve više ukazuje na to da ćemo morati da živimo sa koronom i da ćemo morati sa našim partnerima da pronađemo način da taj izazov prevaziđemo, a ono što je za sad jedino sigurno da pomaže to su vakcine i to je vakcinacija", istakao je Lončar.

Ko je primio Fajzera primio je

Ko je primio Fajzera primio je

[emoji53]







... Shiit has hit the fan

Biće valjda makar domaćeg Sputnjika koji je svakako bolja vakcina.

 

Pa da ponovimo:

 

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Ipak, postoji jasna razlika u odgovoru na primenu Sinofarm vakcine u različitim starosnim grupama. Primećen je značajno slabiji antitelni odgovor kod osoba starijih od 65 godina, posebno u grupi starijih od 70 godina i to muškog pola, sa čestom pojavom potpunog izostanka specifičnih antitela u cirkulaciji.

blic.rs/vesti/drustvo/fajzer-vakcina-efikasnost-kineska-sinopharm-ruska-sputnjik/egdvkl1

jutros u dz savski venac primila fajzera posle dve kineske. nije bilo gužve ali vraćaju one kojima nije isteklo 6 meseci od prethodne vakcine. 

58 minutes ago, Friend said:

Ko je primio Fajzera primio je

za par godina, kad udje u siroku primenu neka efikasna vakcina, otporna na sojeve, primace se po privatnim klinikama, a uvozice je... pa znamo ko.

ostalo kinez.

mada bi i on dao vise nego adekvatan odgovor na recimo 90% vakcinisanih.