Coronavirus Covid-19 - opšta tema

[ronin]

Kako se objašnjava ovaj potez Borisa Džonsona da se ukinu sve mere od maski na dalje?

[Dankan Ajdaho]

Dovoljan broj vakcinisanih/prokuženih.

[Jozef K.]

Plus biće smenjen, pa se ne obazire više na kritike.

[Shitgenstein]

3 hours ago, ronin said:

Kako se objašnjava ovaj potez Borisa Džonsona da se ukinu sve mere od maski na dalje?

Conservative MP Andrew Bridgen says Boris Johnson has “lost the moral authority to lead the country”, following revelations of lockdown-breaking Downing Street parties.

 

[Shitgenstein]

https://www.euronews.com/2022/01/24/covid-europe-could-be-moving-towards-a-kind-of-pandemic-endgame-says-who

 

Dr Kluge added COVID could become a seasonal disease in the months to come.

"It's plausible that the region is moving towards a kind of pandemic endgame," he explained, adding that Omicron could infect 60% of Europeans by March.

 

Once the current surge of Omicron currently sweeping across Europe subsides, "there will be for quite some weeks and months a global immunity, either thanks to the vaccine or because people have immunity due to the infection, and also lowering seasonality".

"We anticipate that there will be a period of quiet before COVID-19 may come back towards the end of the year, but not necessarily the pandemic coming back," Dr Kluge added.

The Omicron variant, which studies have shown is more contagious than Delta but generally leads to less severe infection among vaccinated people, has raised long-awaited hopes that COVID is starting to shift from a pandemic to a more manageable endemic illness like seasonal flu.

But Dr Kluge cautioned that it was still too early to consider the coronavirus endemic.

"There is a lot of talk about endemic but endemic means ... that it is possible to predict what's going to happen. This virus has surprised us more than once so we have to be very careful," Dr Kluge added.

[Have_Fun]

Warsaw Zoo passed very sad news on Monday as snow leopardess Ayana died after a long and exhausting battle. The animal died due to circulatory and respiratory system failure which had been caused by COVID-19.

According to the zoo, the leopardess was infected by a human. This was not the first case of a snow leopard testing positive for coronavirus, as cases have been recorded in the USA, as well as in Europe.

https://tvn24.pl/tvn24-news-in-english/warsaw-zoo-snow-leopardess-ayana-dies-due-to-covid-19-complications-5571650

[Indy]

E jebenti nisam to baš ni morao da pročitam

[vememah]

 

Quote

COVID-19: endemic doesn’t mean harmless
Rosy assumptions endanger public health — policymakers must act now to shape the years to come.
Aris Katzourakis

The word ‘endemic’ has become one of the most misused of the pandemic. And many of the errant assumptions made encourage a misplaced complacency. It doesn’t mean that COVID-19 will come to a natural end.

To an epidemiologist, an endemic infection is one in which overall rates are static — not rising, not falling. More precisely, it means that the proportion of people who can get sick balances out the ‘basic reproduction number’ of the virus, the number of individuals that an infected individual would infect, assuming a population in which everyone could get sick. Yes, common colds are endemic. So are Lassa fever, malaria and polio. So was smallpox, until vaccines stamped it out.

In other words, a disease can be endemic and both widespread and deadly. Malaria killed more than 600,000 people in 2020. Ten million fell ill with tuberculosis that same year and 1.5 million died. Endemic certainly does not mean that evolution has somehow tamed a pathogen so that life simply returns to ‘normal’.

As an evolutionary virologist, it frustrates me when policymakers invoke the word endemic as an excuse to do little or nothing. There’s more to global health policy than learning to live with endemic rotavirus, hepatitis C or measles.

Stating that an infection will become endemic says nothing about how long it might take to reach stasis, what the case rates, morbidity levels or death rates will be or, crucially, how much of a population — and which sectors — will be susceptible. Nor does it suggest guaranteed stability: there can still be disruptive waves from endemic infections, as seen with the US measles outbreak in 2019. Health policies and individual behaviour will determine what form — out of many possibilities — endemic COVID-19 takes.

Soon after the Alpha variant emerged and spread in late 2020, I argued that, unless infections were suppressed, viral evolution would be fast and unpredictable, with the emergence of more variants with different and potentially more-dangerous biological characteristics. Since then, public-health systems have struggled under the highly transmissible and more-virulent Delta variant, and now there is Omicron, with its substantial ability to evade the immune system, causing reinfections and breakthroughs. Beta and Gamma were also highly dangerous, but did not spread to the same extent.

The same virus can cause endemic, epidemic or pandemic infections: it depends on the interplay of a population’s behaviour, demographic structure, susceptibility and immunity, plus whether viral variants emerge. Different conditions across the world can allow more-successful variants to evolve, and these can seed new waves of epidemics. These seeds are tied to a region’s policy decisions and capacity to respond to infections. Even if one region reaches an equilibrium — be that of low or high disease and death — that might be disturbed when a new variant with new characteristics arrives.

COVID-19 is, of course, not the world’s first pandemic. The fact that immune systems have evolved to cope with constant infections, and the traces of viral genetic material embedded in our own genomes from ancient viral infections, are testament to such evolutionary battles. It is likely that some viruses went ‘extinct’ on their own and still caused high rates of mortality on the way out.

There is a widespread, rosy misconception that viruses evolve over time to become more benign. This is not the case: there is no predestined evolutionary outcome for a virus to become more benign, especially ones, such as SARS-CoV-2, in which most transmission happens before the virus causes severe disease. Consider that Alpha and Delta are more virulent than the strain first found in Wuhan, China. The second wave of the 1918 influenza pandemic was far more deadly than the first.

Much can be done to shift the evolutionary arms race in humanity’s favour. First, we must set aside lazy optimism. Second, we must be realistic about the likely levels of death, disability and sickness. Targets set for reduction should consider that circulating virus risks giving rise to new variants. Third, we must use — globally — the formidable weapons available: effective vaccines, antiviral medications, diagnostic tests and a better understanding of how to stop an airborne virus through mask wearing, distancing, and air ventilation and filtration. Fourth, we must invest in vaccines that protect against a broader range of variants.

The best way to prevent more, more-dangerous or more-transmissible variants from emerging is to stop unconstrained spread, and that requires many integrated public-health interventions, including, crucially, vaccine equity. The more a virus replicates, the greater the chance that problematic variants will arise, most probably where spread is highest. The Alpha variant was first identified in the United Kingdom, Delta was first found in India and Omicron in southern Africa — all places where spread was rampant.

Thinking that endemicity is both mild and inevitable is more than wrong, it is dangerous: it sets humanity up for many more years of disease, including unpredictable waves of outbreaks. It is more productive to consider how bad things could get if we keep giving the virus opportunities to outwit us. Then we might do more to ensure that this does not happen.

 

https://www.nature.com/articles/d41586-022-00155-x

 

Edited January 25, 2022 by vememah

[vememah]

 

[Budja]

https://www.bmj.com/content/376/bmj.o102?fbclid=IwAR3hOyoa3w4rM32Jjsz5NcrwD8qaM64_O9kYQrFeomVj0dRfEZalyM2ztus

 

Transparencija podataka: "Raw data" (a ne vec filtrirani podaci i deskriptivna statistika) treba da budu dostupni.

 

Covid-19 vaccines and treatments: we must have raw data, now

 

Quote

Covid-19 vaccines and treatments: we must have raw data, now

BMJ 2022; 376 doi: https://doi.org/10.1136/bmj.o102 (Published 19 January 2022)

 

Today, despite the global rollout of covid-19 vaccines and treatments, the anonymised participant level data underlying the trials for these new products remain inaccessible to doctors, researchers, and the public—and are likely to remain that way for years to come.16 This is morally indefensible for all trials, but especially for those involving major public health interventions.

Pfizer’s pivotal covid vaccine trial was funded by the company and designed, run, analysed, and authored by Pfizer employees. The company and the contract research organisations that carried out the trial hold all the data.17 And Pfizer has indicated that it will not begin entertaining requests for trial data until May 2025, 24 months after the primary study completion date, which is listed on ClinicalTrials.gov as 15 May 2023 (NCT04368728).

The lack of access to data is consistent across vaccine manufacturers.16 Moderna says data “may be available … with publication of the final study results in 2022.”18 Datasets will be available “upon request and subject to review once the trial is complete,” which has an estimated primary completion date of 27 October 2022 (NCT04470427).

As of 31 December 2021, AstraZeneca may be ready to entertain requests for data from several of its large phase III trials.19 But actually obtaining data could be slow going. As its website explains, “timelines vary per request and can take up to a year upon full submission of the request.”20

The BMJ supports vaccination policies based on sound evidence. As the global vaccine rollout continues, it cannot be justifiable or in the best interests of patients and the public that we are left to just trust “in the system,” with the distant hope that the underlying data may become available for independent scrutiny at some point in the future. The same applies to treatments for covid-19. Transparency is the key to building trust and an important route to answering people’s legitimate questions about the efficacy and safety of vaccines and treatments and the clinical and public health policies established for their use.

 

[mareeee]

Šta kriju?

[אַף אֶחָד]

Kod mene u januaru, do sada 200 mrtvih. Od pocetka pandemije sve zajedno - 1300. Omicron je kao lakse grip.

[braca]

3 hours ago, mareeee said:

Šta kriju?

 

Just now, chandra said:

Kod mene u januaru, do sada 200 mrtvih. Od pocetka pandemije sve zajedno - 1300. Omicron je kao lakse grip.

Pa umiru od vakcine.

 

Pametnom dosta

[Krampa]

12 minutes ago, chandra said:

Kod mene u januaru, do sada 200 mrtvih. Od pocetka pandemije sve zajedno - 1300. Omicron je kao lakse grip.

sta laksi, jos se preporucuje. 93, 2 % omnikon varijanta. kod nas stalno 800+ u bolnici, 200k testiranih dnevno, 40k pozitivnih dnevno, 15+ preminulih.  60% dobilo 3 vakcine.

data kaze da je malo laksi grip, idemo dalje. smanjuju restrikcije, cak nema vise ono "bio u bliskom kontaktu", djecu testiraju dva puta u skolama ali nema vise karantina za okolinu, samo za zarazenog.

 

eh sada, kada se statistika pogleda malo bolje. u zadnjih 7 dana je hospitalizovano 120 dece izmedju 0-2 godine. ca 300 mladinh izmedju 20-39 godina, i naravno ostalih 250+ po ostalim stariosnim  grupama. 37 nevakcinisanih hospitalizovano na 100k zarazenih, 19 vakcinisanih na 100k. od pocetka padnemije od korone preminulo sve skupa 3500+ ljudi od toga 170 u grupi izmedju 0-59 godina.

sve ima, sve se zna ali kako se postaviti prema sve tome i kako se ponasati ostaje nepoznato

[Indy]

7 minutes ago, Krampa said:

kako se postaviti prema sve tome i kako se ponasati ostaje nepoznato

 

Dobra maska, 3x vax, razuman izbor lokacija za mešanje s drugim ljudima (ako se već mora)... Pa, šta ti bob udeli.